Centrifugation Centrifugation is a process that involves the use of the centrifugal force for the separation of mixtures

Principle of centrifugation :

Principle of centrifugation

Slide 5:

If a particle (mass = m kg) spins in a centrifuge
(radius r, m) at a velocity (v, m s-1) then the centrifugal
force (F, N) acting on the particle equals m v2/r.
The same particle experiences gravitational force
(G, Newton) = m g (where g = acceleration due to gravity) F = m v2/r
F= centrifugal force Centrifugal force (F)

Centrifugal effect (C) :

Centrifugal effect (C) The centrifugal effect (C) is the ratio of these
two forces, so C = F/G, i.e. C indicates how much
greater F is than G
Centrifugal effect, C= Force acting in radial direction Gravitational force

Slide 7:

Consider a body of mass ‘m” kg rotating in a circular path of radius “r” at a velocity of “v”
Centrifugal force =f= mv2/r
Same body is experiencing gravitational force, it can be expressed as “G= mg ,
where g = acceleration due to gravity, and m= mass Centrifugal effect (C) = F/G
= mv2 /mgr
(v = 2 π r n )
c = (2π r n)2/ g r
= 4 π2r n2/ g
(d= r/2)
= 2 π2 d n2/ g
(g = 9.807)
C = 2.013 d n2

Centrifugal effect, C= 2.013 n2d :

Centrifugal effect, C= 2.013 n2d n= speed of rotation( revolution per second of centrifuge)
d= diameter of rotation
So we can say……….
Centrifugal effect is directly proportional to diameter of rotation
Centrifugal effect is directly proportional to (speed of rotation)2

Classification of centrifuges :

Classification of centrifuges There are two main types of centrifuge used to achieve separation on an industrial scale,
Filtration centrifuge: Those using perforated baskets, which perform a filtration-type operation (work like a spin-dryer) and
(2) Sedimentation centrifuge : Those with a solid walled vessel, where particles sediment towards the wall under the influence of the centrifugal force

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